⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL23167502 | 1.00 | TTR (0.60) | — | |
| Dioxane SCHEMBL15422680 | 0.95 | TTR (0.55) | — | |
| Oxirane SCHEMBL20224024 | 0.95 | — | — | |
| Dioxane SCHEMBL28112516 | 0.86 | TTR (0.55) | — | |
| Dioxane SCHEMBL23167499 | 0.84 | ALDH1A1 (0.57) | — | |
| Tetrahydrofuran SCHEMBL9077806 | 0.82 | ALDH1A1 (0.67) | — | |
| Methylene Chloride SCHEMBL9077808 | 0.82 | — | — | |
| Dioxane SCHEMBL26110321 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL40243 | 0.82 | — | — | |
| Dioxane SCHEMBL29028444 | 0.82 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111219-B | Hydrophily long wavelength's dihydro porphin light, sound sensitiser and the preparation method and application thereof | 大连理工大学 | 2018-10-16 | — | — | CN | claimed |
| CN-104744553-A | Structural modification method for carbonyl in 11th site and carbonyl in 30th site of glycyrrhetinic acid | LI YUSHAN | 2015-07-01 | — | — | CN | claimed |
| WO-2012042534-A2 | PROCESSES FOR THE PREPARATION OF R-SITAGLIPTIN AND INTERMEDIATES THEREOF | GLENMARK GENERICS LIMITED (IN) | 2012-04-05 | — | — | WO | claimed |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2007-08-02 | — | — | US | claimed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | claimed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | claimed |
| CN-1070647-A | Preparation has the method for optically active false bufotoxin amidoalcohol | WEIYAN SUN (CN) | 1993-04-07 | — | — | CN | claimed |
| CN-118307379-A | Method for synthesizing chiral dialkyl alcohol ester by nickel-catalyzed olefin cross-hydrogenation dimerization | 南方科技大学 | 2024-07-09 | — | — | CN | disclosed |
| US-12030856-B2 | Potassium channel inhibitors | ACESION PHARMA APS (DK) | 2024-07-09 | — | — | US | disclosed |
| CN-114040916-B | Boron compound and organic light-emitting element comprising same | SFC株式会社 | 2024-06-28 | — | — | CN | disclosed |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SPRINGWORKS THERAPEUTICS, INC. | 2024-06-13 | — | — | US | disclosed |
| CN-113354725-B | Caliper antigen and preparation method and application thereof | 杭州隆基生物技术有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20240140912-A1 | ABIETANES AND METHODS OF MAKING AND USING THE SAME | NATIONAL INSTITUTES OF HEALTH | 2024-05-02 | — | — | US | disclosed |
| US-4091016-A | Thiosulfenylcarbamoyl halides | UNION CARBIDE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4082747-A | CHEMICAL PROCESS | MALLINCKRODT, INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4064227-A | Radioimmunoassay method for the determination of cardiotonic glycosides | MALLINCKRODT, INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-4032338-A | HOLOGRAPHIC RECORDING MEDIUM EMPLOYING A PHOTOCONDUCTIVE LAYER AND A LOW MOLECULAR WEIGHT MICROCRYSTALLINE POLYMERIC LAYER | RCA CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4012253-A | Holographic recording medium | RCA CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3998815-A | LABILE; DRUGS | INTERX RESEARCH CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |