SCHEMBL4282709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4279320	0.89	HTR4 (0.58)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4279851	0.86	KCNH2 (0.57)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4271427	0.85	MEN1 (0.60)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4274668	0.85	KCNH2 (0.56)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4270039	0.85	KCNH2 (0.73)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4278165	0.83	CACNA1I (0.71)	KCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL7804998	0.83	KDM4E (0.67)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL1436130	0.80	KCNH2 (0.51)	KCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL4269360	0.80	KCNH2 (0.63)	KCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL4280632	0.80	CACNA1I (0.72)	KCNH2CACNA1HCYP2D6CACNA1IDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.