SCHEMBL4282743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19113450	0.95	KCNH2 (0.53)	KCNH2CACNA1IALDH1A1MCHR1CCR2
	SCHEMBL4280522	0.94	KCNH2 (0.52)	KCNH2CACNA1IALDH1A1CCR2CACNA1G
	SCHEMBL4275404	0.90	KCNH2 (0.60)	KCNH2CACNA1IALDH1A1CACNA1GCACNA1H
	SCHEMBL4282723	0.89	KCNH2 (0.56)	KCNH2CACNA1IALDH1A1MCHR1CCR2
	SCHEMBL4276456	0.89	KCNH2 (0.55)	KCNH2CACNA1IALDH1A1MCHR1CCR2
	SCHEMBL19112657	0.88	KCNH2 (0.64)	KCNH2CACNA1IALDH1A1MCHR1CACNA1G
	SCHEMBL19112825	0.87	KCNH2 (0.53)	KCNH2CACNA1IALDH1A1MCHR1CCR2
	SCHEMBL4271303	0.85	KCNH2 (0.58)	KCNH2CACNA1IMCHR1HTR1AADRA2A
	SCHEMBL4284052	0.85	KCNH2 (0.60)	KCNH2CACNA1IMCHR1CCR2CACNA1G
	SCHEMBL4284054	0.85	KCNH2 (0.60)	KCNH2CACNA1IMCHR1CCR2CACNA1G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.