SCHEMBL4282823

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4274696	0.93	KCNH2 (0.48)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL14770041	0.91	GSK3B (0.52)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4279464	0.90	KCNH2 (0.49)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4270009	0.89	KCNH2 (0.48)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4272474	0.87	KCNH2 (0.55)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL19113045	0.87	CARM1 (0.56)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL19112804	0.85	KCNH2 (0.53)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4276648	0.85	KCNH2 (0.52)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4271586	0.85	KCNH2 (0.52)	KCNH2CACNA1ICCR3CCR2CHRM4
	SCHEMBL4278753	0.84	CACNA1I (0.72)	KCNH2CACNA1ILMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.