SCHEMBL4274696

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4282823	0.93	KCNH2 (0.52)	KCNH2CACNA1ICCR2CHRM4CCR3
	SCHEMBL14770041	0.91	GSK3B (0.52)	KCNH2CACNA1ICCR2CHRM4CCR3
	SCHEMBL15353966	0.90	CACNA1I (0.48)	KCNH2CACNA1ICCR2CCR3HTR7
	SCHEMBL4270009	0.90	KCNH2 (0.48)	KCNH2CACNA1ICCR2CHRM4CCR3
	SCHEMBL4279464	0.89	KCNH2 (0.49)	KCNH2CACNA1ICCR2CHRM4CCR3
	SCHEMBL4277358	0.89	CHRM2 (0.52)	KCNH2CACNA1ICCR2CHRM4HDAC6
	SCHEMBL19113045	0.87	CARM1 (0.56)	KCNH2CACNA1ICCR2CHRM4CCR3
	SCHEMBL4280558	0.86	CACNA1I (0.66)	KCNH2CACNA1ICCR2HTR7LMNA
	SCHEMBL4274989	0.86	CCR2 (0.56)	KCNH2CACNA1ICCR2ALDH1A1POLB
	SCHEMBL4277744	0.86	KMT2A (0.55)	KCNH2CACNA1ICCR2HTR7HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.