Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689399 | 0.84 | KDM5A (0.33) | CA12CA1CA9DNM1 | |
| SCHEMBL7682621 | 0.78 | KDM5A (0.37) | — | |
| SCHEMBL17164846 | 0.77 | CA12 (0.48) | CA12CA1CA2CA9MGLL | |
| Thiourea SCHEMBL17164885 | 0.75 | CA12 (0.47) | CA12CA1CA2CA9MGLL | |
| SCHEMBL10770104 | 0.73 | CA12 (0.41) | CA12CA1CA2CA9MGLL | |
| SCHEMBL6006539 | 0.72 | EPHX1 (0.36) | DNM1 | |
| SCHEMBL6006518 | 0.70 | EPHX1 (0.49) | — | |
| SCHEMBL6008437 | 0.69 | EPHX1 (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL6850051 | 0.69 | CA12 (0.41) | CA12CA1 | |
| SCHEMBL8523734 | 0.68 | ADH1C (0.39) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155828-A1 | METHODS OF DETECTING PROSTATE CANCER | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-06-18 | — | — | US | disclosed |
| US-20060171947-A1 | Serine/threonine hydrolase proteins and screening assays | BURNHAM INSTITUTE | 2006-08-03 | — | — | US | disclosed |
| US-7083987-B2 | Activity based probe analysis | ACTIVX BIOSCIENCES, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20030175986-A1 | Activity based probe analysis | ACTIVX BIOSCIENCES, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20030096328-A1 | Serine/threonine hydrolase proteins and screening assays | BURNHAM INSTITUTE | 2003-05-22 | — | — | US | disclosed |
| WO-2003023355-A2 | SERINE/THREONINE HYDROLASE PROTEINS AND SCREENING ASSAYS | THE BURNHAM INSTITUTE (US) | 2003-03-20 | — | — | WO | disclosed |