SCHEMBL8523734

SCHEMBL8523734

CCCCCN([C]=O)NC=O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADH1C P00326 4/20 0.39
ADH1A P07327 4/20 0.39
ADH1B P00325 3/20 0.39
ADH7 P40394 3/20 0.39
ADH4 P08319 3/20 0.39
EPHX1 P07099 1/20 0.39
DNM1 Q05193 3/20 0.33
TSHR P16473 3/20 0.32
ALDH1A1 P00352 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28097039 0.85
SCHEMBL11647784 0.74 ADH1C (0.50) ADH1CADH1AADH1BADH7ADH4
SCHEMBL7688794 0.73 FAAH (0.40) ADH1CADH1AADH4DNM1TSHR
SCHEMBL11397519 0.72 ADH1A (0.43) ADH1CADH1AADH1BADH7ADH4
SCHEMBL11647781 0.72 EPHX1 (0.39) ADH1CADH1AADH1BADH7ADH4
SCHEMBL8523736 0.71 ADH1C (0.41) ADH1CADH1AADH1BADH7ADH4
SCHEMBL97180 0.71 DNM1 (0.43) ADH1CADH1AADH1BADH7ADH4
SCHEMBL7682621 0.71 KDM5A (0.37) TSHRALDH1A1
SCHEMBL28166981 0.69 ADH1C (0.45) ADH1CADH1AADH1BADH7ADH4
SCHEMBL27870138 0.69 ADH1C (0.45) ADH1CADH1AADH1BADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922711-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, SHOCK OR ANALGESICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-07-13 US claimed