Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913086 | 0.83 | CA1 (0.47) | GLACA1CA2CA12CA9 | |
| SCHEMBL1082207 | 0.79 | GLA (0.69) | GLACA12CA9SMN1; SMN2LMNA | |
| SCHEMBL21753821 | 0.74 | GLA (0.54) | GLAHTTCNR2PYCR1 | |
| SCHEMBL3407737 | 0.72 | ALDH1A1 (0.53) | CA1CA2CA12CA9CA4 | |
| SCHEMBL13913087 | 0.70 | CA12 (0.48) | GLACA1CA2CA12CA9 | |
| SCHEMBL6776106 | 0.70 | GLA (0.56) | GLASMN1; SMN2HTTTAS2R14MEN1 | |
| SCHEMBL30212484 | 0.70 | MEN1 (0.42) | GLASMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL21646275 | 0.69 | SMN1; SMN2 (0.50) | CA1CA2CA12CA9CA4 | |
| SCHEMBL30212577 | 0.69 | ESR1 (0.44) | GLASMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL3539406 | 0.68 | CYP3A4 (0.52) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1765910-A2 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | The Scripps Research Institute (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005046-A9 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | SCRIPPS RESEARCH INST (US) | 2006-03-09 | — | — | WO | disclosed |
| WO-2006005046-A2 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | CROCC, JAK3, APOBEC3A | GLA 4386/4885CA1 3864/4885CA2 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.