SCHEMBL4283090

SCHEMBL4283090

C=C(C(=O)Cl)c1cccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
MMP3 P08254 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
PTPN1 P18031 1/20 0.50
CDC25B P30305 1/20 0.50
PLK1 P53350 1/20 0.50
DEGS1 O15121 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
HPGD P15428 3/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HSP90AA1 P07900 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 5/20 0.44
POLB P06746 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35405 0.82 NR4A1 (0.64) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL23069113 0.82 NR4A1 (0.59) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL28349079 0.81 NR4A1 (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL31623008 0.81 NR4A1 (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL1380734 0.81 NR4A1 (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL10865795 0.81 NR4A1 (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL996420 0.80 NR4A1 (0.61) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL4201604 0.79 PTK2B (0.60) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL29808434 0.79 NR4A1 (0.65) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL123694 0.79 NR4A1 (0.65) PTK2BL3MBTL1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009131274-A1 SYNTHESIS OF PHOTOINITIATOR FREE REACTIVE MESOGENS BASED ON TRIPHENYLENE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2009-10-29 WO disclosed
WO-1992000547-A1 POLYMERIC COMPOSITIONS BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) 1992-01-09 WO disclosed
US-4151303-A Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions BOEHRINGER MANNHEIM GMBH (DE) 1979-04-24 US disclosed
US-3993684-A PHOTOSENSITIVE ACRYLIC ESTER POLYMERS WESTERN LITHO PLATE & SUPPLY CO. (US) 1976-11-23 US disclosed