SCHEMBL4201604

SCHEMBL4201604

C=C(Cl)c1cccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
MMP3 P08254 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
PTPN1 P18031 1/20 0.47
CDC25B P30305 1/20 0.47
PLK1 P53350 1/20 0.47
CYP1A2 P05177 3/20 0.44
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
POLB P06746 3/20 0.41
KMT2A Q03164 3/20 0.41
CNR2 P34972 2/20 0.41
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378880 0.81 NR4A1 (0.58) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL1869296 0.81 PTK2B (0.59) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL27564962 0.81 ALDH1A1 (0.56) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL4283090 0.79 PTK2B (0.58) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL5999394 0.79 PTK2B (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL146735 0.79 NR4A1 (0.61) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL29808434 0.77 NR4A1 (0.65) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL123694 0.77 NR4A1 (0.65) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL27755163 0.77 NR4A1 (0.65) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL5497000 0.77 PTK2B (0.55) PTK2BL3MBTL1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4035447-A Fire resistant polymer composition KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-07-12 US claimed
US-8822592-B2 Aqueous emulsion polymer as dispersant BASF SE (DE) 2014-09-02 US disclosed
US-20090234062-A1 Aqueous emulsion polymer as dispersant CIBA SPECIALTY CHEMICALS CORP. 2009-09-17 US disclosed
EP-1444302-B1 LEVELLING AGENT AND ANTI-CRATERING AGENT CIBA HOLDING INC (CH) 2009-06-17 EP disclosed
CN-100436552-C Levelling agent and anti-cratering agent EFKA ADDITIVES B V (CH) 2008-11-26 CN disclosed
CN-100364649-C Aqueous emulsion polymer as dispersant EFKA ADDITIVES B V (NL) 2008-01-30 CN disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
EP-1562696-B1 AQUEOUS EMULSION POLYMER AS DISPERSANT CIBA SC HOLDING AG (CH) 2006-03-29 EP disclosed
CN-1713955-A Aqueous emulsion polymers as dispersants EFKA ADDITIVES B V (NL) 2005-12-28 CN disclosed
WO-1999024510-A1 WATER DISPERSIBLE POLYMERIC COMPOSITIONS S.C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-05-20 WO disclosed
WO-1999024485-A2 POLYMERIC COMPOSITIONS, AND THE PREPARATION AND USE THEREOF S.C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-05-20 WO disclosed
WO-1998054256-A1 CROSS-LINKABLE SURFACE COATINGS AND PROCESS OF PREPARATION S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1998-12-03 WO disclosed
US-4588656-A Method of preparing a magnetic recording medium FUJI PHOTO FILM CO., LTD. (JP) 1986-05-13 US disclosed
EP-0044835-A1 CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1982-02-03 EP disclosed
WO-1981001289-A1 CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT BAMFORD C 1981-05-14 WO disclosed
US-4263420-A Process for preparing styrenic resins LABOFINA, S. A. (BE) 1981-04-21 US disclosed
US-4260466-A SIMULTANEOUS VAPOR DEPOSITION OF A FERROMAGNETIC MATERIAL AND A POLYMER OR MONOMER FUJI PHOTO FILM CO., LTD. (JP) 1981-04-07 US disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-4035447-A Fire resistant polymer composition KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-07-12 US disclosed