Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276046 | 0.94 | PTGDR2 (0.41) | FFAR4FFAR1CNR1PDE3BPDE3A | |
| SCHEMBL4272479 | 0.81 | PTGDR2 (0.48) | FFAR4FFAR1PDE3BPDE3APDE2A | |
| SCHEMBL4275437 | 0.80 | FFAR4 (0.39) | FFAR4FFAR1PPARGPPARAPPARD | |
| SCHEMBL4272358 | 0.80 | PTGDR2 (0.57) | FFAR1PPARGPPARACYP4F2CYP4A11 | |
| SCHEMBL4281384 | 0.78 | PTGDR2 (0.39) | PPARGPTGDR2 | |
| SCHEMBL3180242 | 0.76 | PTGDR2 (0.64) | FFAR4FFAR1PPARGPPARAPPARD | |
| SCHEMBL3172653 | 0.75 | PTGDR2 (0.64) | FFAR4FFAR1PPARGPPARACNR1 | |
| SCHEMBL4275920 | 0.74 | PTGDR2 (0.45) | FFAR4FFAR1PDE3BPDE3APDE2A | |
| SCHEMBL4276043 | 0.73 | PTGDR2 (0.43) | FFAR4FFAR1PPARGPPARAPPARD | |
| SCHEMBL3169234 | 0.70 | PTGDR2 (0.72) | FFAR4FFAR1PPARGCNR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |