Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081295 | 0.93 | BACE1 (0.34) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1081296 | 0.92 | BACE1 (0.34) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1081297 | 0.91 | HPGD (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL3696265 | 0.85 | BACE1 (0.34) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL3693933 | 0.85 | BACE1 (0.34) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL3694157 | 0.85 | LTA4H (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1193793 | 0.85 | LTA4H (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1193791 | 0.85 | LTA4H (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1177679 | 0.83 | HPGD (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 | |
| SCHEMBL1177677 | 0.83 | HPGD (0.35) | BACE1ALDH1A1HPGDTSHRACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |