SCHEMBL4283903

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4282669	0.90	CXCR3 (0.43)	ACP1CXCR3NAMPTHCRTR1HCRTR2
	SCHEMBL4276917	0.82	CACNA1I (0.56)	KCNH2CACNA1I
	SCHEMBL4274878	0.81	CXCR3 (0.45)	ACP1CXCR3NAMPTRHOCRHOA
	SCHEMBL19112799	0.80	CXCR3 (0.42)	ACP1CXCR3NAMPTHCRTR1HCRTR2
	SCHEMBL19112564	0.80	CXCR3 (0.41)	CXCR3NAMPTHCRTR1HCRTR2RHOC
	SCHEMBL4271123	0.78	CACNA1I (0.57)	KCNH2CACNA1I
	SCHEMBL4271321	0.75	CXCR3 (0.43)	ACP1CXCR3NAMPTRHOCRHOA
	SCHEMBL15353982	0.74	CXCR3 (0.39)	ACP1CXCR3NAMPTRHOCRHOA
	SCHEMBL4277786	0.73	MEN1 (0.47)	ACP1CXCR3NAMPTRHOCRHOA
	SCHEMBL4280629	0.73	CXCR3 (0.45)	ACP1CXCR3NAMPTHCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.