Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160021 | 0.85 | MRGPRX4 (0.52) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL8431628 | 0.85 | MRGPRX4 (0.52) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL9823873 | 0.84 | MRGPRX4 (0.42) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL30104807 | 0.84 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL6743790 | 0.84 | MRGPRX4 (0.71) | MRGPRX4ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL7916623 | 0.84 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL31730474 | 0.80 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL4146898 | 0.80 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL2287859 | 0.78 | SLC6A4 (0.56) | MRGPRX4ALDH1A1MEN1KMT2ASLC6A4 | |
| SCHEMBL15969101 | 0.78 | MAOB (0.46) | ALDH1A1LRRK2SLC6A4HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1335903-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | MRGPRX4 1467/4885ALDH1A1 171/4885MEN1 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.