Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104807 | 1.00 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL4284174 | 0.84 | MRGPRX4 (0.52) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL4160021 | 0.84 | MRGPRX4 (0.52) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL8431628 | 0.84 | MRGPRX4 (0.52) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL6743790 | 0.82 | MRGPRX4 (0.71) | MRGPRX4ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31730574 | 0.80 | MAOB (0.42) | ALDH1A1LRRK2THRATHRBSLC6A4 | |
| SCHEMBL1542659 | 0.80 | MAOB (0.42) | ALDH1A1LRRK2THRATHRBSLC6A4 | |
| SCHEMBL17594985 | 0.80 | MAOB (0.49) | ALDH1A1THRATHRBSLC6A4MAOB | |
| SCHEMBL31730474 | 0.79 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 | |
| SCHEMBL4146898 | 0.79 | MRGPRX4 (0.51) | MRGPRX4ALDH1A1MEN1KMT2ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-6225320-B1 | TREATMENT OF PAIN, INFLAMMATION, MIGRAINE, EMESIS AND POSTTHERPETIC NEURALGIA | MERCK SHARP & DOHME LTD. (GB) | 2001-05-01 | — | — | US | disclosed |
| EP-0989987-A1 | SPIRO-AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998054187-A1 | SPIRO-AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1998-12-03 | — | — | WO | disclosed |