SCHEMBL4284588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4276698	0.85	S1PR1 (0.42)	S1PR1S1PR3S1PR5BRD4BRPF1
	SCHEMBL4276096	0.84	GSK3B (0.42)	S1PR1S1PR3S1PR5BRD4BRPF1
	SCHEMBL4277053	0.81	LCLAT1 (0.36)	SYKMKNK2PDE4BMAPK1CDC7
	SCHEMBL20780184	0.78	SMN1; SMN2 (0.38)	S1PR1S1PR3MAPK1LMNASMN1; SMN2
	SCHEMBL4278473	0.78	S1PR1 (0.36)	S1PR1S1PR3S1PR5PDE4BMAPK1
	SCHEMBL4552121	0.78	SMN1; SMN2 (0.35)	SYKMTORMKNK2PDE4BMAPK1
	SCHEMBL4276856	0.78	PDE4B (0.35)	S1PR1S1PR3S1PR5PTGS2PDE4B
	SCHEMBL13701432	0.77	MAPT (0.39)	PTGS2MAPK1THRBLMNAHTT
	SCHEMBL4277707	0.77	S1PR1 (0.37)	S1PR1S1PR3S1PR5PDE4BPPARG
	SCHEMBL4271374	0.77	S1PR1 (0.37)	S1PR1S1PR3S1PR5PDE4BPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.