SCHEMBL4277053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20780184	0.95	SMN1; SMN2 (0.38)	LCLAT1SCN9AKDM4ENPSR1MAPK1
	SCHEMBL4276646	0.85	PPARG (0.38)	LCLAT1NFE2L2KDM4ENPSR1MAPK1
	SCHEMBL4269836	0.84	GSK3B (0.40)	KDM4ECDK2GSK3BALDH1A1KMT2A
	SCHEMBL4552121	0.84	SMN1; SMN2 (0.35)	LCLAT1KDM4ESYKCDC7PLK4
	SCHEMBL4275002	0.84	ADRA1D (0.35)	LCLAT1NFE2L2KDM4ENPSR1PPARG
	SCHEMBL4639466	0.83	TPH1 (0.36)	LCLAT1NFE2L2KDM4ENPSR1PPARG
	SCHEMBL4273666	0.82	LCLAT1 (0.34)	LCLAT1NFE2L2KDM4EPPARGPPARA
	SCHEMBL20780191	0.82	LCLAT1 (0.34)	LCLAT1NFE2L2KDM4EPPARGPPARA
	SCHEMBL4284588	0.81	S1PR1 (0.38)	SYKCDC7PLK4DYRK3ROCK2
	SCHEMBL4286018	0.80	PPARG (0.37)	LCLAT1KDM4ENPSR1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.