SCHEMBL4552121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4278398	0.85	GSK3B (0.41)	SMN1; SMN2KMT2AALDH1A1MAPTMEN1
	SCHEMBL4277053	0.84	LCLAT1 (0.36)	KMT2AALDH1A1LCLAT1SYKHTT
	SCHEMBL4286018	0.84	PPARG (0.37)	SMN1; SMN2KMT2AALDH1A1MAPTMEN1
	SCHEMBL20780184	0.82	SMN1; SMN2 (0.38)	SMN1; SMN2KMT2AALDH1A1MAPTMEN1
	SCHEMBL4269836	0.79	GSK3B (0.40)	KMT2AALDH1A1MAPTMEN1KDM4E
	SCHEMBL4270647	0.79	PPARG (0.39)	LCLAT1PPARGPPARAKLKB1
	SCHEMBL4276646	0.78	PPARG (0.38)	SMN1; SMN2KMT2AALDH1A1MAPTMEN1
	SCHEMBL4284588	0.78	S1PR1 (0.38)	SMN1; SMN2MTORSYKHTTMAPK1
	SCHEMBL4275002	0.77	ADRA1D (0.35)	KMT2AALDH1A1MAPTMEN1LCLAT1
	SCHEMBL20780191	0.77	LCLAT1 (0.34)	KMT2AALDH1A1MAPTMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.