N-Acetylproline

N-Acetylproline

SCHEMBL428477

CC(=O)N1CCC[C@@H]1C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 10/20 0.54
REN P00797 3/20 0.54
LMNA P02545 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CYP2C19 P33261 1/20 0.54
KDM4E B2RXH2 1/20 0.54
F2 P00734 1/20 0.54
LTA4H P09960 1/20 0.54
MAPT P10636 1/20 0.54
PEPD P12955 1/20 0.54
ALOX15 P16050 1/20 0.54
PTGS1 P23219 1/20 0.54
HTR2A P28223 1/20 0.54
PTGS2 P35354 1/20 0.54
HRH1 P35367 1/20 0.54
THPO P40225 1/20 0.54
PMP22 Q01453 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Acetylproline SCHEMBL358379 1.00 ACE (0.54) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL428476 1.00 ACE (0.54) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL6469164 0.98 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL1375025 0.98 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL1375029 0.98 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
SCHEMBL5860164 0.94 ACE (0.49) ACERENLMNAHSD17B10CYP2C19
SCHEMBL7054783 0.94 ACE (0.49) ACERENLMNAHSD17B10CYP2C19
SCHEMBL1840265 0.94 ACE (0.49) ACERENLMNAHSD17B10CYP2C19
SCHEMBL19566169 0.92 ACE (0.56) ACERENLMNAHSD17B10CYP2C19
SCHEMBL22423638 0.92 ACE (0.56) ACERENLMNAHSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119517408-A Method for establishing death prediction model of new-onset type 2 diabetes and application 中南大学湘雅二医院 2025-02-25 CN claimed
CN-118542948-A Nanometer medicinal preparation for treating sepsis, and its preparation method and application 四川大学 2024-08-27 CN claimed
CN-116514679-A Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method 南京工业大学 2023-08-01 CN claimed
CN-113395898-A Compositions for treating citrus disease and promoting yield enhancement of row crops 斯波根生物技术公司 2021-09-14 CN claimed
EP-3546940-B1 BIOMARKERS RELATED TO KIDNEY FUNCTION AND METHODS USING THE SAME METABOLON INC (US) 2021-02-17 EP claimed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
CN-110997695-A Novel compounds that activate the Nrf2 pathway 阿尔米雷尔有限公司 2020-04-10 CN claimed
CN-110885358-A Vaccine for preventing tumor recurrence and metastasis and application method thereof 浙江爱睦世医学科技有限公司 2020-03-17 CN claimed
EP-3546940-A1 BIOMARKERS RELATED TO KIDNEY FUNCTION AND METHODS USING THE SAME Metabolon, Inc. (US) 2019-10-02 EP claimed
US-20120214817-A1 UROTENSIN II RECEPTOR ANTAGONISTS MARYANOFF BRUCE E (US) 2012-08-23 US claimed
US-6027890-A DETECTING LIGAND BINDING BY INCUBATING TAGGED MEMBERS WITH BIOLOGICAL SAMPLE, SEPARATING BOUND FROM UNBOUND MEMBERS, CLEAVING TAG, THEN DETECTING BY NON-FLUORESCENT SPECTROSCOPY OR POTENTIOMETRY RAPIGENE, INC. (US) 2000-02-22 US claimed
EP-0962464-A2 Methods and compositions for detecting binding of ligand pair using non-fluorescent label Rapigene, Inc. (US) 1999-12-08 EP claimed
EP-0722459-B1 HEMOREGULATORY PENTA- OR HEXAPEPTIDES NYCOMED IMAGING AS (NO) 1998-12-23 EP claimed
EP-0868535-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES Rapigene, Inc. (US) 1998-10-07 EP claimed
EP-0850320-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL DARWIN MOLECULAR CORPORATION (US) 1998-07-01 EP claimed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
WO-1997027327-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL RAPIGENE, INC. (US) 1997-07-31 WO claimed
EP-0508133-B1 Method of preparation of L-Carnitine from D,L-Carnitine nitrile salts DEGUSSA (DE) 1995-02-15 EP claimed
US-5284872-A Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof SCHWARZ PHARMA AG (DE) 1994-02-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214817-A1 UROTENSIN II RECEPTOR ANTAGONISTS UTS2R, PLAUR, BDKRB2 ACE 120/4885REN 31/4885LMNA 2503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.