SCHEMBL7054783

SCHEMBL7054783

CC(=O)N1CCCC[C@@H]1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 9/20 0.49
REN P00797 3/20 0.49
LMNA P02545 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 1/20 0.49
F2 P00734 1/20 0.49
LTA4H P09960 1/20 0.49
MAPT P10636 1/20 0.49
PEPD P12955 1/20 0.49
ALOX15 P16050 1/20 0.49
PTGS1 P23219 1/20 0.49
HTR2A P28223 1/20 0.49
PTGS2 P35354 1/20 0.49
HRH1 P35367 1/20 0.49
THPO P40225 1/20 0.49
PMP22 Q01453 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5860164 1.00 ACE (0.49) ACERENLMNAHSD17B10CYP2C19
SCHEMBL1840265 1.00 ACE (0.49) ACERENLMNAHSD17B10CYP2C19
SCHEMBL7908918 0.98 ACE (0.47) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL428476 0.94 ACE (0.54) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL428477 0.94 ACE (0.54) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL358379 0.94 ACE (0.54) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL1375025 0.92 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL1375029 0.92 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
N-Acetylproline SCHEMBL6469164 0.92 ACE (0.53) ACERENLMNAHSD17B10CYP2C19
SCHEMBL19566169 0.86 ACE (0.56) ACERENLMNAHSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0723586-B1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID DARWIN DISCOVERY LTD (GB) 1999-12-22 EP claimed
US-5733754-A ACYLASE WHICH HYDROLYZING N-ACETYLPIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1998-03-31 US claimed
EP-0723586-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID Chiroscience Limited (GB) 1996-07-31 EP claimed
WO-1995010604-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1995-04-20 WO claimed
CN-115151544-B Beta-lactamase inhibitor and preparation thereof 宁夏农林科学院 2024-08-16 CN disclosed
US-20230365561-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2023-11-16 US disclosed
EP-4146650-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION Ningxia Academy of Agriculture and Forestry Sciences (CN) 2023-03-15 EP disclosed
CN-115151544-A Beta-lactamase inhibitors and preparation thereof 宁夏农林科学院 2022-10-04 CN disclosed
WO-2022047603-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2022-03-10 WO disclosed
US-20200392107-A1 CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2020-12-17 US disclosed
US-20200392107-A1 CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2020-12-17 US disclosed
EP-3747879-A1 CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF Toray Industries, Inc. (JP) 2020-12-09 EP disclosed
US-5733754-A ACYLASE WHICH HYDROLYZING N-ACETYLPIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1998-03-31 US disclosed
US-5733754-A ACYLASE WHICH HYDROLYZING N-ACETYLPIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1998-03-31 US disclosed
EP-0784603-A2 RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF Chiroscience Limited (GB) 1997-07-23 EP disclosed
EP-0723586-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID Chiroscience Limited (GB) 1996-07-31 EP disclosed
EP-0723586-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID Chiroscience Limited (GB) 1996-07-31 EP disclosed
WO-1996011173-A2 RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF CHIROSCIENCE LIMITED (GB) 1996-04-18 WO disclosed
WO-1995010604-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1995-04-20 WO disclosed
WO-1995010604-A1 ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID CHIROSCIENCE LIMITED (GB) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392107-A1 CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF NPR3, SLC10A1, CNR2 ACE 1515/4885REN 393/4885LMNA 4220/4885
US-20230365561-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION MGAM, LCT, GANAB ACE 22/4885REN 192/4885LMNA 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.