Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122492 | 0.87 | PTGDR2 (0.65) | PTGDR2HDAC7BACE1LMNAMAPK1 | |
| SCHEMBL122491 | 0.87 | PTGDR2 (0.65) | PTGDR2HDAC7BACE1LMNAMAPK1 | |
| SCHEMBL4974893 | 0.85 | PTGDR2 (0.63) | PTGDR2HDAC7BACE1LMNATDP1 | |
| SCHEMBL20573244 | 0.84 | PTGDR2 (0.45) | PTGDR2LMNA | |
| Benzamide SCHEMBL21771965 | 0.83 | PTGDR2 (0.53) | PTGDR2HDAC7LMNATDP1L3MBTL1 | |
| SCHEMBL20573256 | 0.81 | BACE1 (0.52) | BACE1LMNAMAPK1TDP1L3MBTL1 | |
| SCHEMBL20573401 | 0.81 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL17796980 | 0.81 | PTGDR2 (0.43) | PTGDR2BACE1BCAT2 | |
| SCHEMBL28060842 | 0.80 | PTGDR2 (0.57) | PTGDR2HDAC7BACE1LMNAMAPK1 | |
| SCHEMBL7647143 | 0.80 | LMNA (0.50) | PTGDR2LMNAMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |
| EP-3029026-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | Dong-A ST Co., Ltd. (KR) | 2016-06-08 | — | — | EP | disclosed |
| EP-2063897-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Deciphera Pharmaceuticals, LLC. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008034008-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2008-03-20 | — | — | WO | disclosed |