Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797020 | 0.88 | CYP1A1 (0.53) | BACE1HDAC8TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL31652642 | 0.85 | HDAC8 (0.48) | BACE1HDAC8HTTMEN1KMT2A | |
| SCHEMBL20573396 | 0.85 | PDE4D (0.51) | BACE1HDAC8HDAC4HDAC2LMNA | |
| SCHEMBL20573264 | 0.85 | TUBB4A (0.50) | BACE1HDAC8HDAC4HDAC2LMNA | |
| SCHEMBL20573163 | 0.82 | CTSA (0.44) | BACE1HDAC8HDAC4HDAC2HTT | |
| SCHEMBL20573252 | 0.82 | CTSA (0.43) | BACE1HDAC8HDAC4HDAC2L3MBTL1 | |
| SCHEMBL4077193 | 0.81 | BACE1 (0.51) | BACE1HDAC8HDAC4HDAC2L3MBTL1 | |
| SCHEMBL4284793 | 0.81 | PTGDR2 (0.61) | BACE1L3MBTL1LMNAMAPK1TDP1 | |
| SCHEMBL29572032 | 0.80 | KDM4E (0.64) | BACE1HDAC8HDAC4HDAC2L3MBTL1 | |
| SCHEMBL835688 | 0.80 | KDM4E (0.64) | BACE1HDAC8HDAC4HDAC2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |