Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.55 |
| ▸ | FNTB | P49356 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682773 | 0.89 | FNTA (0.67) | FNTAFNTBCYP3A4 | |
| SCHEMBL7208289 | 0.87 | FNTA (0.41) | FNTAFNTBCYP3A4NTRK1 | |
| SCHEMBL1683558 | 0.83 | FNTA (0.79) | FNTAFNTBCYP3A4 | |
| SCHEMBL5736481 | 0.80 | FNTA (0.61) | FNTAFNTBCYP3A4 | |
| SCHEMBL6173232 | 0.79 | FNTA (0.50) | FNTAFNTBCYP3A4 | |
| SCHEMBL1667242 | 0.78 | FNTA (0.65) | FNTAFNTBCYP3A4 | |
| Hydrochloric Acid SCHEMBL6807778 | 0.78 | FNTA (0.55) | FNTAFNTBCYP3A4 | |
| SCHEMBL1683530 | 0.76 | CYP3A4 (0.67) | FNTAFNTBCYP3A4 | |
| SCHEMBL3499579 | 0.76 | FNTA (0.67) | FNTAFNTBCYP3A4 | |
| SCHEMBL5510621 | 0.75 | FNTA (0.74) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094839-B1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS WITH (IN VIVO) RADIOSENSITIZING PROPERTIES | JANSSEN PHARMACEUTICA NV (BE) | 2003-05-02 | — | — | EP | claimed |
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |