Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.41 |
| ▸ | FNTB | P49356 | 12/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284857 | 0.87 | FNTA (0.55) | FNTAFNTBNTRK1CYP3A4 | |
| SCHEMBL5737090 | 0.84 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL5735112 | 0.77 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6172596 | 0.76 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL1682773 | 0.76 | FNTA (0.67) | FNTAFNTBCYP3A4 | |
| SCHEMBL6171352 | 0.74 | FNTA (0.45) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL1683558 | 0.72 | FNTA (0.79) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL5736856 | 0.71 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4RORC | |
| SCHEMBL6174338 | 0.71 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4RORC | |
| Hydrochloric Acid SCHEMBL6807778 | 0.68 | FNTA (0.55) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094839-B1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS WITH (IN VIVO) RADIOSENSITIZING PROPERTIES | JANSSEN PHARMACEUTICA NV (BE) | 2003-05-02 | — | — | EP | claimed |