Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.53 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282437 | 0.90 | FNTA (0.51) | RORCFNTAFNTB | |
| SCHEMBL4284855 | 0.88 | FNTA (0.48) | RORCFNTAFNTB | |
| SCHEMBL6174101 | 0.87 | FNTA (0.67) | RORCFNTAFNTB | |
| SCHEMBL1682751 | 0.84 | FNTA (0.61) | RORCFNTAFNTB | |
| SCHEMBL3518891 | 0.78 | FNTA (0.62) | RORCFNTAFNTB | |
| SCHEMBL6170839 | 0.78 | FNTA (0.66) | RORCFNTAFNTB | |
| SCHEMBL6169332 | 0.77 | FNTA (0.84) | RORCFNTAFNTB | |
| SCHEMBL7815392 | 0.77 | FNTA (0.84) | RORCFNTAFNTB | |
| SCHEMBL6171864 | 0.77 | FNTA (0.72) | RORCFNTAFNTB | |
| SCHEMBL3499579 | 0.77 | FNTA (0.67) | RORCFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |