Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 15/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171333 | 0.88 | FNTA (0.62) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL4284860 | 0.88 | RORC (0.53) | FNTAFNTBRORC | |
| SCHEMBL1682751 | 0.84 | FNTA (0.61) | FNTAFNTBRORCCNR1PGGT1B | |
| SCHEMBL4282437 | 0.83 | FNTA (0.51) | FNTAFNTBRORCCNR1PGGT1B | |
| SCHEMBL4290048 | 0.81 | FNTA (0.58) | FNTAFNTBRORCCNR1PGGT1B | |
| SCHEMBL6172187 | 0.80 | FNTA (0.64) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL3527417 | 0.78 | FNTA (0.62) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL6169281 | 0.78 | FNTA (0.79) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL3518891 | 0.75 | FNTA (0.62) | FNTAFNTBRORCCNR1 | |
| SCHEMBL6174101 | 0.75 | FNTA (0.67) | FNTAFNTBRORCPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |