Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203617 | 0.86 | GFER (1.00) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL28003279 | 0.85 | GFER (0.68) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2224601 | 0.85 | GFER (0.68) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL13064774 | 0.85 | GFER (0.68) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2073499 | 0.85 | GFER (0.68) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6343767 | 0.81 | LMNA (0.55) | GFERMAPTLMNATP53POLB | |
| SCHEMBL13680922 | 0.81 | GFER (0.62) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL12409160 | 0.81 | GFER (0.72) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL15348929 | 0.81 | GFER (0.72) | GFERMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2056124 | 0.81 | GFER (0.72) | GFERMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153536-A1 | 1-AZA-BICYCLO [2.2.2] OCTANE DERIVATIVES USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | ARGENTA DISCOVERY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |