Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127254 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13658262 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13619595 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL1127429 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL1127987 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13619619 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL1128142 | 0.78 | KDM4E (0.46) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13658303 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13658294 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 | |
| SCHEMBL13658301 | 0.78 | KDM4E (0.50) | ALDH1A1CYP1A2CYP3A4IDO1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | EIF2AK2, HAVCR2, HDGF | ALDH1A1 1614/4885CYP1A2 1659/4885CYP3A4 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.