SCHEMBL4285320

SCHEMBL4285320

CC(=O)OCc1cc(O)c(Cc2ccc(OC(C)C)cc2)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
KDM4A O75164 1/20 0.44
MAPT P10636 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
HTR2A P28223 11/20 0.41
TSPO P30536 1/20 0.38
IDH1 O75874 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4291912 0.87 NFKB1 (0.42) MAPTIDH1MAOBALDH1A1
SCHEMBL4279412 0.85 MAPT (0.43) POLBMAPTIDH1MAOAMAOB
SCHEMBL4286495 0.84 IDH1 (0.41) IDH1MAOBKDM4EALDH1A1
SCHEMBL4286864 0.84 IDH1 (0.41) POLBIDH1MAOBALDH1A1
SCHEMBL4279610 0.83 POLB (0.48) POLBKDM4AMAPTKDM4CHTR2A
SCHEMBL4279693 0.83 SLC5A1 (0.45) IDH1MAOAMAOBL3MBTL1KDM4E
SCHEMBL4289375 0.82 HTR2A (0.41) HTR2AIDH1MAOAMAOBALDH1A1
SCHEMBL4292523 0.81 PARP10 (0.43) POLBHTR2AMAOAMAOB
SCHEMBL4279556 0.80 POLB (0.39) POLBHTR2AMAOBALDH1A1
SCHEMBL4288111 0.79 IDH1 (0.38) IDH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 POLB 4872/4885KDM4A 1867/4885MAPT 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.