Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289375 | 0.84 | HTR2A (0.41) | IDH1CYP3A4ALDH1A1NAAA | |
| SCHEMBL4286864 | 0.84 | IDH1 (0.41) | IDH1CYP3A4ALDH1A1 | |
| SCHEMBL4286495 | 0.84 | IDH1 (0.41) | IDH1CYP3A4ALDH1A1 | |
| SCHEMBL4289255 | 0.83 | CYP3A4 (0.47) | IDH1CYP3A4ALDH1A1QDPRSLC18A3 | |
| SCHEMBL4291912 | 0.82 | NFKB1 (0.42) | IDH1CYP3A4ALDH1A1 | |
| SCHEMBL4285009 | 0.81 | CYP3A4 (0.36) | CYP3A4ALDH1A1QDPRSLC18A3ESR2 | |
| SCHEMBL4285014 | 0.80 | CYP3A4 (0.35) | CYP3A4SLC18A3ESR2FFAR4MRGPRX4 | |
| SCHEMBL4279412 | 0.80 | MAPT (0.43) | IDH1ALDH1A1 | |
| SCHEMBL4285320 | 0.79 | POLB (0.44) | IDH1ALDH1A1 | |
| SCHEMBL4279693 | 0.78 | SLC5A1 (0.45) | IDH1ALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472937-A | Benzylphenylglucopyranoside Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |
| US-20090137499-A1 | BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2048150-A1 | BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137499-A1 | BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | IDH1 722/4885CYP3A4 534/4885ALDH1A1 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.