Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285547 | 0.90 | KDM4E (0.37) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4281106 | 0.89 | BTK (0.39) | RAB9AALDH1A1KDM4EGAAGRIN1 | |
| SCHEMBL4293729 | 0.88 | MAPK1 (0.41) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL4282070 | 0.86 | NPC1 (0.48) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4287638 | 0.85 | LMNA (0.50) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4285550 | 0.84 | MEN1 (0.40) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4284656 | 0.82 | FFAR1 (0.42) | ALDH1A1MEN1KMT2AKDM4EFFAR4 | |
| SCHEMBL4294041 | 0.82 | HCRTR1 (0.40) | ALDH1A1MEN1KMT2AKDM4EFFAR4 | |
| SCHEMBL4297224 | 0.81 | SYK (0.42) | — | |
| Hydrochloric Acid SCHEMBL4290984 | 0.80 | SCN9A (0.38) | RAB9AALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | RAB9A 1247/4885ALDH1A1 388/4885MEN1 1254/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | RAB9A 1247/4885ALDH1A1 388/4885MEN1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.