Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902367 | 0.78 | PTPN1 (0.34) | ALDH1A1GSTP1CYP1A2 | |
| SCHEMBL11733124 | 0.71 | ALDH1A1 (0.33) | ALDH1A1GSTP1 | |
| SCHEMBL1340149 | 0.70 | — | — | |
| SCHEMBL29008399 | 0.69 | GSTP1 (0.35) | GSTP1 | |
| SCHEMBL17866738 | 0.68 | TDP1 (0.41) | GSTP1CYP1A2 | |
| SCHEMBL6902175 | 0.68 | GSTP1 (0.31) | GSTP1 | |
| SCHEMBL11763707 | 0.68 | GSTP1 (0.53) | ALDH1A1GSTP1 | |
| SCHEMBL28602056 | 0.67 | GSTP1 (0.40) | GSTP1 | |
| SCHEMBL1044406 | 0.67 | — | — | |
| SCHEMBL11211634 | 0.67 | GSTP1 (0.45) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-06-18 | — | — | US | disclosed |
| WO-2005092324-A1 | GINKGOLIDE COMPOUNDS, COMPOSITIONS, EXTRACTS, AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | PYGB, NLN, GRIN3B | ALDH1A1 3738/4885GSTP1 914/4885CYP1A2 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.