Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL125344 | 0.77 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL8621256 | 0.77 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28090651 | 0.77 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL13575633 | 0.77 | TSHR (0.40) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4289192 | 0.75 | ALDH1A1 (0.43) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL874011 | 0.75 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL646397 | 0.75 | — | — | |
| Hexaethylene Glycol SCHEMBL875412 | 0.75 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL854457 | 0.75 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Tetraethylene Glycol SCHEMBL236335 | 0.75 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153034-A1 | PHOSPHORAMIDATE FLAME RETARDANTS | EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) | 2009-12-23 | — | — | WO | disclosed |