SCHEMBL4285656

SCHEMBL4285656

OC[C@H]1O[C@H](Oc2ccc(Cc3ccccc3)cc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 1/20 0.68
▸ SLC5A2 P31639 7/20 0.65
▸ SLC5A1 P13866 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1037902 1.00 TYR (0.68) TYRSLC5A2SLC5A1
SCHEMBL28716182 0.89 TYR (0.86) TYRSLC5A2SLC5A1
SCHEMBL3797056 0.88 TYR (0.74) TYR
SCHEMBL4307510 0.88 TYR (0.74) TYR
SCHEMBL1007043 0.88 TYR (0.74) TYR
SCHEMBL9148547 0.88 TYR (0.74) TYR
SCHEMBL16785948 0.88 TYR (0.74) TYR
SCHEMBL21189542 0.88 TYR (0.74) TYR
SCHEMBL21477447 0.88 TYR (0.74) TYR
SCHEMBL4651473 0.88 TYR (0.74) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952206-B1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION TAISHO PHARMACEUTICAL CO LTD (JP) 2018-10-24 — — EP disclosed
US-10022389-B2 Prophylactic or therapeutic drug for constipation TAISHO PHARMACEUTICAL CO., LTD. (JP) 2018-07-17 — — US disclosed
US-20150374735-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-12-31 — — US disclosed
EP-2952206-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION Taisho Pharmaceutical Co., Ltd. (JP) 2015-12-09 — — EP disclosed
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 — — CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 — — US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 TYR 1270/4885SLC5A2 2/4885SLC5A1 1/4885
US-20150374735-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION SLC5A1, SLC5A2, SLC10A2 TYR 4437/4885SLC5A2 2/4885SLC5A1 1/4885
US-10022389-B2 Prophylactic or therapeutic drug for constipation SLC5A1, SLC5A2, SLC10A2 TYR 4437/4885SLC5A2 2/4885SLC5A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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