Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13981710 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL3797056 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL1007043 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL4307510 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL1004929 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL4651473 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL9148547 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL21477447 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL21189542 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 | |
| SCHEMBL29051487 | 1.00 | TYR (0.74) | TYRPOLBATMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004222-B2 | Small molecule ice recrystallization inhibitors and methods of use thereof | THE UNIVERSITY OF OTTAWA (CA) | 2018-06-26 | — | — | US | disclosed |
| US-9648869-B2 | Small molecule ice recrystallization inhibitors and methods of use thereof | THE UNIVERSITY OF OTTAWA (CA) | 2017-05-16 | — | — | US | disclosed |
| US-20150373968-A1 | Small Molecule Ice Recrystallization Inhibitors And Methods Of Use Thereof | THE UNIVERSITY OF OTTAWA (CA) | 2015-12-31 | — | — | US | disclosed |
| US-20150157010-A1 | SMALL MOLECULE ICE RECRYSTALLIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF OTTAWA (CA) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150157010-A1 | SMALL MOLECULE ICE RECRYSTALLIZATION INHIBITORS AND METHODS OF USE THEREOF | PYGL, GYS2, GDI2 | TYR 2483/4885POLB 2607/4885ATM 2018/4885 |
| US-10004222-B2 | Small molecule ice recrystallization inhibitors and methods of use thereof | MCL1, IDH3B, IDH3A | TYR 3135/4885POLB 2780/4885ATM 2574/4885 |
| US-20150373968-A1 | Small Molecule Ice Recrystallization Inhibitors And Methods Of Use Thereof | MCL1, DCX, IDH3B | TYR 2787/4885POLB 3122/4885ATM 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.