⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78690 | 0.77 | — | — | |
| SCHEMBL1903594 | 0.77 | — | — | |
| SCHEMBL29216007 | 0.76 | — | — | |
| SCHEMBL270695 | 0.76 | — | — | |
| SCHEMBL270696 | 0.76 | — | — | |
| Acetic Acid SCHEMBL28182484 | 0.72 | — | — | |
| SCHEMBL5567728 | 0.71 | — | — | |
| SCHEMBL35001 | 0.71 | — | — | |
| SCHEMBL2925945 | 0.71 | — | — | |
| SCHEMBL84341 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117964623-A | Targeted protein degradation compound and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117715897-A | Compounds and their use as CD38 inhibitors | 南京艾美斐生物医药科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | LEADINGTAC PHARMACEUTICAL (SHAOXING) CO., LTD. (CN) | 2023-07-27 | — | — | US | claimed |
| CN-116262739-A | Nitrogen-containing aryl derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-16 | — | — | CN | claimed |
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | claimed |
| CN-116135851-A | Aromatic amine compound and application thereof | 武汉众诚康健生物医药科技有限公司 | 2023-05-19 | — | — | CN | claimed |
| US-20230061118-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-03-02 | — | — | US | claimed |
| CN-113521079-A | Use of IRAK4 inhibitors for the treatment of ALI/ARDS | 上海领泰生物医药科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| WO-2021116005-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2021-06-17 | — | — | WO | claimed |
| WO-2021115560-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2021-06-17 | — | — | WO | claimed |
| WO-2021000755-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | 清华大学 | 2021-01-07 | — | — | WO | claimed |
| CN-111683950-A | AhR modulators | 伊迪亚生物科学有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-110759963-A | Condensed ring compound and preparation method and application thereof | 中山大学 | 2020-02-07 | — | — | CN | claimed |
| WO-2019041340-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR 1 (LPAR1) INHIBITOR COMPOUNDS | ELI LILLY AND COMPANY (US) | 2019-03-07 | — | — | WO | claimed |
| EP-0831836-A4 | SYNTHETIC CATALYTIC FREE RADICAL SCAVENGERS USEFUL AS ANTIOXIDANTS FOR PREVENTION AND THERAPY OF DISEASE | EUKARION INC (US) | 2000-09-27 | — | — | EP | claimed |
| EP-0831836-A1 | SYNTHETIC CATALYTIC FREE RADICAL SCAVENGERS USEFUL AS ANTIOXIDANTS FOR PREVENTION AND THERAPY OF DISEASE | EUKARION, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040149-A1 | SYNTHETIC CATALYTIC FREE RADICAL SCAVENGERS USEFUL AS ANTIOXIDANTS FOR PREVENTION AND THERAPY OF DISEASE | EUKARION, INC. (US) | 1996-12-19 | — | — | WO | claimed |