SCHEMBL4285827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4275349	0.98	GSK3B (0.41)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4273674	0.97	LMNA (0.42)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4275383	0.95	BRD4 (0.40)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4275012	0.93	GSK3B (0.41)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4279514	0.93	PDE4B (0.42)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4282801	0.90	HPGD (0.46)	GSK3BCDK2HPGDCYP1A2CYP3A4
	SCHEMBL19182630	0.88	LMNA (0.43)	GSK3BCDK2DHODHHPGDCYP1A2
	SCHEMBL4275305	0.88	DHODH (0.46)	DHODHHPGDMAPTKMT2AHSD17B10
	SCHEMBL4276064	0.88	DHODH (0.46)	DHODHHPGDMAPTKMT2AHSD17B10
	SCHEMBL4269836	0.85	GSK3B (0.40)	GSK3BCDK2HPGDCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.