SCHEMBL4273674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4285827	0.97	GSK3B (0.41)	LMNAMAPTMEN1TP53KMT2A
	SCHEMBL4275349	0.95	GSK3B (0.41)	LMNAMAPTMEN1TP53KMT2A
	SCHEMBL4275383	0.92	BRD4 (0.40)	LMNAMAPTSMN1; SMN2MEN1KMT2A
	SCHEMBL4275012	0.90	GSK3B (0.41)	LMNAMAPTMEN1TP53KMT2A
	SCHEMBL4279514	0.90	PDE4B (0.42)	MAPTALOX15GSK3BCDK2DHODH
	SCHEMBL4272656	0.88	HPGD (0.45)	LMNAMAPTSMN1; SMN2MEN1USP2
	SCHEMBL4280811	0.88	LMNA (0.40)	LMNAMAPTSMN1; SMN2KMT2AGSK3B
	SCHEMBL4270560	0.88	HPGD (0.43)	LMNAMAPTSMN1; SMN2MEN1USP2
	SCHEMBL4273168	0.87	LMNA (0.43)	LMNAMAPTSMN1; SMN2MEN1KMT2A
	SCHEMBL4280728	0.87	GSK3B (0.41)	LMNAGSK3BCDK2HPGDIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.