⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705179 | 0.93 | PDE4B (0.32) | — | |
| SCHEMBL4285437 | 0.88 | USP19 (0.35) | — | |
| SCHEMBL4284990 | 0.88 | HCRTR1 (0.32) | — | |
| SCHEMBL4282156 | 0.87 | RAB9A (0.30) | — | |
| SCHEMBL4289587 | 0.87 | PRMT5 (0.33) | — | |
| SCHEMBL4289022 | 0.86 | POLB (0.32) | — | |
| SCHEMBL4285677 | 0.86 | HCRTR1 (0.39) | — | |
| SCHEMBL4282962 | 0.85 | HCRTR1 (0.34) | — | |
| SCHEMBL4292958 | 0.85 | PRMT5 (0.38) | — | |
| SCHEMBL4284891 | 0.85 | CA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |