Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345536 | 0.77 | HTT (0.41) | MAOBALDH1A1LMNAHTTTAAR1 | |
| SCHEMBL2397031 | 0.75 | ACP3 (0.49) | EPHX1MAOBMAPTHTTMEN1 | |
| SCHEMBL31173731 | 0.75 | MLYCD (0.63) | NR3C2EPHX1LMNAMEN1KMT2A | |
| SCHEMBL1052230 | 0.75 | MLYCD (0.63) | NR3C2EPHX1LMNAMEN1KMT2A | |
| SCHEMBL39835 | 0.73 | TAAR1 (0.56) | KDM4EEPHX1MAOBMAPTALDH1A1 | |
| SCHEMBL9593411 | 0.73 | P2RX1 (0.65) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL30645023 | 0.73 | TAAR1 (0.62) | NR3C2EPHX1MAOBACP3TAAR1 | |
| SCHEMBL185922 | 0.73 | TAAR1 (0.62) | NR3C2EPHX1MAOBACP3TAAR1 | |
| SCHEMBL11749179 | 0.72 | CNR1 (0.61) | KDM4ENR3C2EPHX1MAOBMAPT | |
| SCHEMBL5966615 | 0.72 | PDPK1 (0.43) | EPHX1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | disclosed |