SCHEMBL39835

SCHEMBL39835

O=CCc1cccc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
ACP3 P15309 1/20 0.56
IDO1 P14902 2/20 0.55
HTR2A P28223 2/20 0.53
HTR2B P41595 2/20 0.53
HTR2C P28335 1/20 0.53
MIF P14174 2/20 0.50
MAPT P10636 3/20 0.49
POLB P06746 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
DAO P14920 2/20 0.47
LMNA P02545 2/20 0.47
EPHX1 P07099 1/20 0.47
MAOB P27338 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
ADRA2C P18825 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13377016 0.93 DAO (0.50) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL16398826 0.89 MAOB (0.50) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL13403379 0.85 ALDH1A1 (0.53) IDO1MAPTPOLBKDM4EALDH1A1
SCHEMBL5738726 0.84 MAOB (0.62) ACP3MAPTPOLBALDH1A1MEN1
SCHEMBL5703037 0.84 IDO1 (0.59) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL66607 0.83 TAAR1 (0.61) TAAR1ACP3IDO1HTR2AHTR2B
Formamide SCHEMBL28223716 0.83 TAAR1 (0.51) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL6264578 0.82 HTR2A (0.56) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL3636562 0.82 TAAR1 (0.55) TAAR1ACP3IDO1HTR2AHTR2B
SCHEMBL27986136 0.82 TAAR1 (0.55) TAAR1ACP3IDO1HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
WO-2024245143-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES 赛诺哈勃药业(成都)有限公司 2024-12-05 WO disclosed
EP-4455136-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE Scinnohub Pharmaceutical Co., Ltd. (CN) 2024-10-30 EP disclosed
CN-118510768-A Diazasulfinyl structure-containing compounds and their use in medicine 赛诺哈勃药业(成都)有限公司 2024-08-16 CN disclosed
EP-4373816-A1 INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) Dana-Farber Cancer Institute, Inc. (US) 2024-05-29 EP disclosed
EP-4313973-A1 NOVEL POTASSIUM CHANNEL INHIBITORS Acesion Pharma ApS (DK) 2024-02-07 EP disclosed
WO-2023174836-A1 IMIDAZOLE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS ACESION PHARMA APS (DK) 2023-09-21 WO disclosed
WO-2023116774-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE 赛诺哈勃药业(成都)有限公司 2023-06-29 WO disclosed
US-20230192644-A1 PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-06-22 US disclosed
WO-2001000574-A1 PYRROLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-04 WO disclosed
WO-2000004011-A1 CYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DYSLIPIDAEMIA, ATHEROSCLEROSIS AND DIABETES, PHARMACEUTICAL COMPOSITIONS AND PREPARATION PROCESS MERCK PATENT GMBH (DE) 2000-01-27 WO disclosed
EP-0906307-A1 SUBSTITUTED IMIDAZOLES HAVING CYTOKINE INHIBITORY ACTIVITY Merck & Co., Inc. (US) 1999-04-07 EP disclosed
WO-1997047618-A1 SUBSTITUTED IMIDAZOLES HAVING CYTOKINE INHIBITORY ACTIVITY MERCK & CO., INC. (US) 1997-12-18 WO disclosed
EP-0231003-B1 BASIC SUBSTITUTED PHENYLACETONITRILES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1993-04-07 EP disclosed
US-4968717-A SEROTONIN-AND CALCIUM-ANTAGONISTS BASF AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0231003-A2 Basic substituted phenylacetonitriles, their preparation and medicaments containing them BASF Aktiengesellschaft (DE) 1987-08-05 EP disclosed
US-4289890-A Synthesis of chloromethyldisilanes GORDON ROY G 1981-09-15 US disclosed
US-4264775-A BY DIAZOTIZATION OF ANILINES, REACTING WITH A VINYL ESTER, AND REACTING WITH A SECONDARY AMINE ELI LILLY AND COMPANY (US) 1981-04-28 US disclosed
US-3984400-A 11-Desoxy-16-aryl-ω-tetranorprostaglandins PFIZER INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE BCL9, USP9X, BCL9L TAAR1 4548/4885ACP3 4185/4885IDO1 4260/4885
US-20230192644-A1 PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE IKZF2, IKZF1, NUTF2 TAAR1 3719/4885ACP3 3885/4885IDO1 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.