Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731238 | 0.90 | PIK3CG (0.63) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10044927 | 0.84 | MAPT (0.55) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL18167168 | 0.84 | AGTR1 (0.42) | MAPTPIK3CGALDH1A1 | |
| SCHEMBL4296830 | 0.83 | PIK3CG (0.54) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2733208 | 0.83 | PIK3CG (0.72) | PIK3CGPIK3CD | |
| SCHEMBL4288292 | 0.81 | PIK3CG (0.59) | MAPTPIK3CGPIK3CD | |
| SCHEMBL18167167 | 0.81 | LMNA (0.41) | MAPTPIK3CG | |
| SCHEMBL2721570 | 0.80 | PIK3CG (0.60) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2721975 | 0.79 | PIK3CG (0.63) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4286070 | 0.79 | PIK3CG (0.60) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052102-A1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |