Sugi Predict

Sugi Predict / Compounds / SCHEMBL4286264

SCHEMBL4286264

SCHEMBL4286264

COc1nc(C)nc(NC(N)=O)n1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.46
▸ MAPT P10636 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ CYP1A2 P05177 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ APP P05067 2/20 0.34
▸ ACHE P22303 2/20 0.34
▸ PTK2 Q05397 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499675 0.89 MAPT (0.45) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL8532151 0.85 GAA (0.49) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL13026229 0.84 CYP1A2 (0.53) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL9480478 0.84 GAA (0.47) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL8678377 0.83 GAA (0.42) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL11801853 0.82 KMT2A (0.38) GAAMAPTHTTCYP1A2ALDH1A1
SCHEMBL11802135 0.82 KMT2A (0.38) GAAMAPTHTTCYP1A2KMT2A
SCHEMBL19956431 0.81 GAA (0.45) GAAMAPTHTTNPSR1CYP1A2
SCHEMBL9738027 0.78 GAA (0.43) GAAKDM4E
SCHEMBL7932221 0.78 GAA (0.46) GAAMAPTHTTNPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4530717-A Synergistic herbicidal mixtures of substituted phenylsulfonylurea derivatives and benzthiazol-2-yl-oxyacetic acid N-methylanilide NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-07-23 — — US claimed
CN-106458958-B Herbicidal propynyl-phenyl compounds 先正达参股股份有限公司 2020-07-10 — — CN disclosed
CN-107074755-B Herbicidal compounds 先正达参股股份有限公司 2020-03-17 — — CN disclosed
EP-2882293-B1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID DOW AGROSCIENCES LLC (US) 2019-01-16 — — EP disclosed
US-20090259062-A1 SURFACTANT COMPOSITIONS AND ASSOCIATED METHOD MOMENTIVE PERFORMANCE MATERIALS INC. 2009-10-15 — — US disclosed
EP-1482799-B1 HERBICIDE COMBINATIONS WITH SPECIAL SULFONYLUREAS BAYER CROPSCIENCE AG (DE) 2008-05-21 — — EP disclosed
EP-0378985-A1 Improved glyphosate formulations MONSANTO COMPANY (US) 1990-07-25 — — EP disclosed
US-4530717-A Synergistic herbicidal mixtures of substituted phenylsulfonylurea derivatives and benzthiazol-2-yl-oxyacetic acid N-methylanilide NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090259062-A1 SURFACTANT COMPOSITIONS AND ASSOCIATED METHOD SGMS2, SGMS1, GMNN GAA 2233/4885MAPT 3690/4885HTT 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.