Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CPS1 | P31327 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284654 | 0.92 | CPS1 (0.44) | CPS1MEN1KMT2AGPR119 | |
| SCHEMBL4281655 | 0.83 | KDM4E (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4286140 | 0.82 | HCRTR1 (0.44) | ALDH1A1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL4287557 | 0.81 | ALDH1A1 (0.37) | ALDH1A1CPS1HPGDTSHRHSD17B10 | |
| SCHEMBL4286026 | 0.81 | HPGD (0.49) | ALDH1A1HPGDKMT2AKDM4EMAPT | |
| SCHEMBL4286428 | 0.81 | HCRTR1 (0.47) | ALDH1A1KDM4EMAPTRAB9AHCRTR1 | |
| SCHEMBL4290774 | 0.80 | DRD3 (0.49) | HPGDMEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL4290602 | 0.80 | HCRTR1 (0.39) | ALDH1A1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL4290172 | 0.80 | GPR183 (0.46) | HPGDMEN1KMT2AKDM4EMAPT | |
| SCHEMBL4285580 | 0.80 | CPS1 (0.46) | CPS1KDM4EHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885CPS1 2464/4885HPGD 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.