Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926625 | 0.83 | CNR1 (0.33) | GSK3BGSK3ADYRK1ACLK4 | |
| SCHEMBL4282889 | 0.77 | GSK3B (0.45) | GSK3BGSK3ACLK4 | |
| SCHEMBL2974024 | 0.74 | GSK3B (0.33) | GSK3BGSK3A | |
| SCHEMBL2935929 | 0.73 | GSK3B (0.33) | GSK3BGSK3A | |
| SCHEMBL2932832 | 0.66 | SCN10A (0.33) | — | |
| SCHEMBL2931661 | 0.66 | AHR (0.36) | — | |
| Hydrochloric Acid SCHEMBL4287767 | 0.66 | SCN10A (0.32) | — | |
| SCHEMBL12680833 | 0.66 | GSK3B (0.58) | GSK3BMEN1KMT2AGSK3ADYRK1A | |
| SCHEMBL3617487 | 0.66 | GSK3B (0.65) | GSK3BMEN1KMT2AGSK3ADYRK1A | |
| SCHEMBL1514132 | 0.65 | GSK3B (0.72) | GSK3BMEN1KMT2AGSK3ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | THPO, IL5, TPMT | GSK3B 2707/4885MEN1 2668/4885KMT2A 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.