SCHEMBL428693

SCHEMBL428693

C=C(C)C(=O)OC(COP(=O)([O-])OCC[N+](C)(C)C)OP(=O)([O-])OCC[N+](C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.52
ADRA1D P25100 1/20 0.49
PTAFR P25105 1/20 0.49
HTR1D P28221 1/20 0.49
HTR2C P28335 1/20 0.49
ADRA1B P35368 1/20 0.49
DRD3 P35462 1/20 0.49
TMEM97 Q5BJF2 1/20 0.49
MAPT P10636 1/20 0.46
NR5A2 O00482 1/20 0.45
NR5A1 Q13285 1/20 0.45
AKT1 P31749 2/20 0.43
LMNA P02545 2/20 0.43
PRKD3 O94806 1/20 0.43
PRKCG P05129 1/20 0.43
PRKCB P05771 1/20 0.43
PRKCA P17252 1/20 0.43
PRKCH P24723 1/20 0.43
PRKCI P41743 1/20 0.43
PRKCE Q02156 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14830815 0.91 ADRA1D (0.50) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL1260662 0.86 ADRA1D (0.57) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL1225864 0.86 SMN1; SMN2 (0.53) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL529986 0.83 SMN1; SMN2 (0.46) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL15393235 0.82 AKT1 (0.44) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL2120563 0.82 SMN1; SMN2 (0.52) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL1260814 0.81 ADRA1D (0.57) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL1260833 0.80 ADRA1D (0.61) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL20401677 0.78 SMN1; SMN2 (0.49) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C
SCHEMBL35785 0.78 SMN1; SMN2 (0.49) SMN1; SMN2ADRA1DPTAFRHTR1DHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9052848-A None JP disclosed
CN-118217455-A Sliding member, method for manufacturing same, and artificial joint 京瓷株式会社 2024-06-21 CN disclosed
US-20240010807-A1 METHOD FOR FORMING GRAFT LAYER, METHOD FOR PRODUCING COMPOSITE, AND TREATMENT LIQUID FOR FORMING GRAFT LAYER KYOCERA MEDICAL CORPORATION (JP) 2024-01-11 US disclosed
US-20230416579-A1 AEROSOL RAW MATERIAL COMPOSITION, AEROSOL COMPOSITION, AND AEROSOL PRODUCT AGC Inc. (JP) 2023-12-28 US disclosed
US-11746308-B2 Soft contact lens treatment solution NOF CORPORATION (JP) 2023-09-05 US disclosed
EP-4212560-A1 METHOD FOR FORMING GRAFT LAYER, METHOD FOR PRODUCING COMPOSITE, AND TREATMENT LIQUID FOR FORMING GRAFT LAYER Kyocera Corporation (JP) 2023-07-19 EP disclosed
CN-116096767-A Method for forming graft layer, method for producing composite, and treatment liquid for forming graft layer 京瓷株式会社 2023-05-09 CN disclosed
CN-115917322-A Substance-immobilizing substrate and use thereof 国立研究开发法人理化学研究所 2023-04-04 CN disclosed
EP-3056226-B1 ANTIOXIDATIVE PROSTHETIC MEMBER KYOCERA CORP (JP) 2023-02-22 EP disclosed
US-20230047677-A1 MANUFACTURING METHOD OF SLIDING MEMBER FOR ARTIFICIAL JOINT, SLIDING MEMBER FOR ARTIFICIAL JOINT, AND ARTIFICIAL JOINT KYOCERA MEDICAL CORPORATION (JP) 2023-02-16 US disclosed
US-20110274940-A1 GRAFT POLYMERIZATION METHOD AND PRODUCT OBTAINED THEREBY KYOCERA CORPORATION (JP) 2011-11-10 US disclosed
EP-2380600-A1 POLYMER SLIDING MATERIAL, ARTIFICIAL JOINT MEMBER, MEDICAL APPLIANCE, AND MANUFACTURING METHOD THEREFOR Japan Medical Materials Corporation (JP) 2011-10-26 EP disclosed
EP-2360193-A1 GRAFT POLYMERIZATION METHOD AND PRODUCT OBTAINED THEREBY Japan Medical Materials Corporation (JP) 2011-08-24 EP disclosed
US-20100262237-A1 Biomaterial, Joint Prosthesis Using the Biomaterial and Method of Producing the Same JAPAN MEDICAL MATERIALS CORPORATION (JP) 2010-10-14 US disclosed
EP-2204197-A1 BIOCOMPATIBLE AND LOW-WEAR MATERIAL, ARTIFICIAL JOINT USING THE SAME AND METHOD OF PRODUCING THE SAME Japan Medical Materials Corporation (JP) 2010-07-07 EP disclosed
EP-2174975-A1 HYDROPHILIC POLYOLEFIN SINTERED BODY Asahi Kasei Chemicals Corporation (JP) 2010-04-14 EP disclosed
US-20090306781-A1 High Wear-Resistant Bearing Material and Artificial Joint Replacement Using the Same KYOCERA CORPORATION (JP) 2009-12-10 US disclosed
EP-2002854-A2 BIOMATERIAL, ARTIFICIAL JOINT USING THE SAME AND METHOD OF PRODUCING THE SAME Japan Medical Materials Corporations (JP) 2008-12-17 EP disclosed
EP-1987849-A1 LOW-WEAR SLIDING MEMBER AND ARTIFICIAL JOINT MAKING USE OF THE SAME Japan Medical Materials Corporations (JP) 2008-11-05 EP disclosed
JP-H0952848-A SKIN PREPARATION FOR EXTERNAL USE POLA CHEM IND INC 1997-02-25 JP disclosed