SCHEMBL1260833

SCHEMBL1260833

C=C(C)C(=O)OC(CCCC)COP(=O)([O-])OCC[N+](C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.61
PTAFR P25105 1/20 0.61
HTR1D P28221 1/20 0.61
HTR2C P28335 1/20 0.61
ADRA1B P35368 1/20 0.61
DRD3 P35462 1/20 0.61
TMEM97 Q5BJF2 1/20 0.61
MAPT P10636 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.56
NR5A2 O00482 1/20 0.56
NR5A1 Q13285 1/20 0.56
MAPK1 P28482 3/20 0.55
MEN1 O00255 2/20 0.55
GMNN O75496 2/20 0.55
LMNA P02545 2/20 0.55
BLM P54132 2/20 0.55
KMT2A Q03164 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
PRKD3 O94806 1/20 0.55
PRKCG P05129 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1260814 0.93 ADRA1D (0.57) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL1260662 0.88 ADRA1D (0.57) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL14675019 0.85 ADRA1D (0.55) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10844793 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10852722 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10846439 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10847644 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10846630 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10852153 0.84 ADRA1D (0.81) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL3655243 0.84 ADRA1D (0.61) ADRA1DPTAFRHTR1DHTR2CADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
WO-2023121292-A1 POLYMER COMPOUND AND APPLICATION THEREOF 주식회사 삼양사 2023-06-29 WO claimed
EP-3774310-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2022-07-06 EP claimed
EP-3746820-B1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC (CH) 2022-02-16 EP claimed
US-9084739-B2 Cross-linked copolymer containing phosphorylcholine monomer and cosmetic composition containing same KCI LIMITED (KR) 2015-07-21 US claimed
US-20140288259-A1 SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME KCI CO., LTD. (KR) 2014-09-25 US claimed
EP-2662070-A2 CROSS-LINKED COPOLYMER CONTAINING PHOSPHORYLCHOLINE MONOMER AND COSMETIC COMPOSITION CONTAINING SAME KCI Limited. (KR) 2013-11-13 EP claimed
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same KCI LIMITED (KR) 2013-11-07 US claimed
US-8278097-B2 Method for forming embryoid bodies NOF CORPORATION (JP) 2012-10-02 US claimed
US-20090246871-A1 For forming embryoid bodies from embryonic stem (ES) cells easily and efficiently without complicated technique NOF CORPORATION (JP) 2009-10-01 US claimed
US-20060252148-A1 For forming embryoid bodies from embryonic stem (ES) cells easily and efficiently without complicated technique NOF CORPORATION (JP) 2006-11-09 US claimed
EP-0537972-B1 Treating solution for contact lenses NOF CORP (JP) 1996-07-10 EP claimed
EP-0537972-A1 Treating solution for contact lenses NOF CORPORATION (JP) 1993-04-21 EP claimed
US-20230350100-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 US disclosed
US-11029446-B2 Method for producing MPS-compatible water gradient contact lenses ALCON INC. (CH) 2021-06-08 US disclosed
EP-0537972-B1 Treating solution for contact lenses NOF CORP (JP) 1996-07-10 EP disclosed
US-5461433-A Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups NOF CORPORATION (JP) 1995-10-24 US disclosed
EP-0537972-A1 Treating solution for contact lenses NOF CORPORATION (JP) 1993-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288259-A1 SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME C1QBP, PCTP, CD59 ADRA1D 2687/4885PTAFR 851/4885HTR1D 3131/4885
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same PHOSPHO1, SGMS1, SGMS2 ADRA1D 2549/4885PTAFR 1310/4885HTR1D 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.