Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.70 |
| ▸ | ADCY10 | Q96PN6 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880327 | 0.84 | AGPAT2 (0.67) | HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL3944554 | 0.82 | HSP90AB1 (1.00) | HSP90AA1HSP90AB1ADCY10ALDH1A1MAPT | |
| SCHEMBL4282248 | 0.79 | AGPAT2 (0.55) | HSP90AA1HSP90AB1ALDH1A1MAPTAGPAT2 | |
| SCHEMBL4277599 | 0.78 | AGPAT2 (0.54) | HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL4291022 | 0.78 | AGPAT2 (0.52) | HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL3951667 | 0.77 | ADCY10 (0.63) | HSP90AA1HSP90AB1ADCY10BCHEMAOA | |
| SCHEMBL4282695 | 0.77 | AGPAT2 (0.67) | HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL4289149 | 0.76 | AGPAT2 (0.53) | HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL13957869 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTTSHRKDM4E | |
| SCHEMBL4277513 | 0.75 | AGPAT2 (0.49) | HSP90AA1HSP90AB1ALDH1A1AGPAT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | CELL THERAPEUTICS, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-7419984-B2 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20040204386-A1 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204386-A1 | Pyrimidines and uses thereof | LPCAT3, LPCAT1, APRT | HSP90AA1 4126/4885HSP90AB1 4236/4885ADCY10 1194/4885 |
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | LPCAT3, LPCAT1, APRT | HSP90AA1 4006/4885HSP90AB1 3829/4885ADCY10 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.