Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773314 | 0.83 | EDNRA (0.42) | EDNRAEDNRB | |
| SCHEMBL4773257 | 0.83 | AGTR1 (0.51) | EDNRAEDNRB | |
| SCHEMBL13574889 | 0.81 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL4771492 | 0.78 | AGTR1 (0.51) | EDNRAEDNRB | |
| SCHEMBL13574892 | 0.77 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL7557151 | 0.77 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL6767700 | 0.77 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL4793147 | 0.77 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL4774477 | 0.76 | AGTR1 (0.53) | EDNRA | |
| SCHEMBL27541757 | 0.76 | ADAM17 (0.40) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155448-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | claimed |