Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293038 | 0.86 | CA1 (0.48) | HCRTR2CA1CA2CA4CA9 | |
| SCHEMBL4293107 | 0.86 | CA1 (0.48) | HCRTR2CA1CA2CA4CA9 | |
| SCHEMBL4288560 | 0.86 | CA1 (0.36) | HCRTR2CA1CA2CA4CA9 | |
| SCHEMBL4294331 | 0.85 | CA1 (0.48) | HCRTR2CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4286205 | 0.83 | HCRTR1 (0.44) | HCRTR2HCRTR1REN | |
| Hydrochloric Acid SCHEMBL4281647 | 0.82 | HCRTR1 (0.46) | HCRTR2CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4294062 | 0.82 | CKS1B (0.40) | HCRTR2CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL4281286 | 0.82 | ABHD6 (0.41) | CA1CA2CA4CA9REN | |
| SCHEMBL4282567 | 0.80 | CA1 (0.39) | HCRTR2CA1CA2CA4CA9 | |
| SCHEMBL8114589 | 0.79 | CA1 (0.38) | HCRTR2CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | HCRTR2 3136/4885CA1 2275/4885CA2 218/4885 |
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | HCRTR2 3136/4885CA1 2275/4885CA2 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.